This may be overly provocative, but it is a legitimate question: Has John McCain had a recent stroke?
This question has been danced around at lot recently -- McCain's age and physical health. He has been quite sparing with his medical records, but other than the melanoma (other than that!) he is reportedly reasonably healthy for a man of his age. He is, however, at risk for a stroke, based on his age and history of high cholesterol and long-term tobacco abuse.
Watch this video, and in particular watch the movements of McCain's left eyelid, brow and forehead muscles.
There is, to my eye, a clear and discernible droop of the left eyebrow and eyelid. There is a small lag when he blinks, there is smoothing of the forehead wrinkles on the left, and the eyebrow does not elevate symmetrically.
Are these clearly visible neurologic deficits consistent with a stroke? Well, sort of but not exactly. There does not appear to be any motor abnormality of the lower part of the face, and his speech is quite clear. Updated: On closer viewing, I think there is some asymmetry of the lower face, with slight smoothing of the nasolabial fold, and reduced excursion of the mouth. It is subtle, and McCain's face is asymmetric at baseline, so it's hard to say whether it is significant. If the impairment were caused by a central lesion (i.e. in the brain), I would generally expect those areas to be affected also, since the motor cortex that controls that area is not usually broken down quite so discretely. But weird stuff can happen in neurology, so it's certainly not conclusive, and a cerebrovascular accident is by no means excluded as a possible cause.
The alternative is that this is a peripheral lesion. The facial muscles are innervated by the Seventh Cranial Nerve, the facial nerve (yellow in this diagram):
The most common cause of facial nerve paralysis is Bell's Palsy, in which the nerve is compressed as it exits the bony skull. Bell's palsy, however, usually affects the entire face, and as I mentioned, there is no evident impairment of the midface and mouth. I might guess that the lesion is confined to the temporal branch of the facial nerve: I believe that McCain had a melanoma lesion removed some years ago from his left temple. Is this deficit related to that surgery? Has it always been present? If so, why are we just noticing it now? It does not seem evident in his convention acceptance speech, only three weeks ago.
What other things can cause this deficit? Ptosis, drooping of the eyelid, can be caused by a lesion of the third cranial nerve, but that should not affect the forehead muscles. There are a large number of things that can cause acquired ptosis, but many are bilateral, which McCain does not have, and I would argue that these are all quite unlikely due to the involvement of the forehead musculature. Ptosis is generally a phenomenon of the eyelid alone.
Bottom line: This looks to my eye like a peripheral injury to the facial nerve, but a stroke cannot be excluded based on what I have seen. Given John McCain's age and the office he seeks, and the patent incompetence of his running mate, he owes the American voters answers to these questions:
- Has he sought medical treatment for this condition?
- If not, why not?
- If so, what evaluation was performed, and what diagnosis was rendered?
- Has he had screening studies for cerebrovascular disease, and what were the results?
[Update: More relevant information posted here.]


40 comments:
Can straight fatigue also cause these symptoms?
Isn't this a largely obvious result of his melanoma surgery? Nerve damage was certainly a possibility, as his wound,"six centimeters by six centimeters," required "sizeable reconstruction." NYT, 5/24/08
I think it is minor and most likely related to the four (!)
proceedures he has had to remove
melonoma from the left side of his face and jaw. On my screen, the symptoms noted are very very minimal. Don't get your hopes up.
Get out and WORK for Obama.
Doc Santa Fe
Could it be botox wearing off unevenly, or asymmetrically applied?
Sad that you're fishing for other reasons to trash-talk McCain, DOCTOR. Perhaps being an ER doc and throwing out "hey, he probably had a stroke" isn't really proper.
Demanding he prove to you that he hasn't had a stroke recently is just disgusting, sorry. You're really turning me off to you as a doctor now even, not just as a political commentator. If some shmuck says the same thing, sure whatever, but when an ER doctor says it with no evidence other than a slightly asymmetric face with no access to his medical records nor assessment, dude, that's crayzee. It's not like you're telling a friend to maybe go get his droopy eye checked out.
Anon 1 & 2:
his last surgery, IIRC, was like 8 years ago. Correct me if I am wrong. This is clearly a new deficit, and it would be strange to have this pop up 8 years later.
Anon 3,
I can't image why he would be on Botox, but yes, a bad botox application could do this in theory.
K,
Spare me your faux outrage. A candidate for the most powerful office in the world with a NEW neurologic deficit ought to explain himself. If it's benign, great, and we can move on. Why the silence?
Let's get a chest x-ray from Obama while we're at it. He's a smoker, you know.
BC
John McCain has Horner's Syndrome, I'm quite confident. This would be from recurrence of his left temporal melanoma. That is, dysfunction of the sympathetic nerves around his left eye. Others have noticed that most of the observed findings are not brand-new, they are WORSE than before.
That is, the underlyhing problem is progressive. This isn't a stroke; strokes start bad and get better. It isn't Bell's Palsy, which also starts bad and gets better.
If the pattern of findings pointed to a brain lesion, MS could be a possibility. But the symptoms suggest a problem external to the brain.
McCain has developed a swelling at the angle of the jaw on the left, below the ear. This is where one would expect to find lymph node involvement if there were a recurrence of melanoma.
Horner's Syndrome has many possible causes, but malignant cancer ranks high among the possibilities:
http://en.wikipedia.org/wiki/Horners_syndrome
Note that McCain has just recently employed a make-up artist for his public appearances; I think it no coincidence that this happens just as these abnormalities are noticed by the public.
McCain has some awareness that something is wrong here; he's taken to shielding the left side of his face from view.
I suspect these worsening neurologic symptoms are the real reason why McCain wanted to cancel the debate.
One has to wonder whether he's had any diagnostic tests. Impossible to know, but I suspect that if he'd gotten an MRI scan, that fact would have leaked out, if not the test results.
He is recognized as an impulsive gambler type, I'd hazard to guess that he's opted to delay any testing until after the election.
Melanoma has some tendency to spread to the brain. McCain has been observed to be fairly easily confused in recent weeks.
Right now, Intrade.com is giving about 55-45 odds on the election, favoring Obama. I'd expect the odds to widen greatly by 11 pm Friday, whether the debate happens or not.
SteveMDFP
I mean, dood, this same post is on DailyKos for crapsakes, Shadowfax. You can't tell me you're not trying to use your authority as an ER doc to stir some sh*t up. John McCain is old, we get it.
If dude had a little word salad and unilateral weakness all of a sudden or can't remember what he did yesterday or 2 minutes ago, yeah, let's talk, but a DROOPY EYELID? Please. I stand by my earlier comment.
Oh and PS, in Wikipedia, McCain is listed as a "well known person with ptosis". Unless they just added that last night or whatever, hm...MAYBE HE'S BEEN DIAGNOSED WITH PTOSIS ALREADY?!
Actually it is very likely that they added it last night after this very post!
Um, that is how that site called Wikipedia, um, works
Actually, that Wikipedia entry WAS added last night--the previous edit of that entry did not have McCain listed on it.
Hey this is great!
Before, while talking medical deficits online the witty retort was "Well, you got your MD from Google!"
This is far more entertaining.
SteveMDFP,
I don't buy Horner's -- the forehead should not be involved with Horner's, and McCain's clearly is.
K,
I'm disappointed in you. You must have seen enough old folks presenting with strokes that you should recognize a facial droop when you see one. Granted, I think this is probably peripheral seventh nerve, and I hope I made that clear in the OP. But I think it's pretty damn newsworthy that a presidential candidate has a *new* and unexplained neurologic deficit.
You should also note that I've kept this a more or less clinical analysis -- no snark about him getting easily confused or having early dementia or any other below-the-belt innuendo. The man's face ain't right, it's new, and it's a fair question to ask why.
Actually, by total coincidence, I viewed a Utube presentation McCaine just did minutes before I came to this site. I sat there fixed on his left eye/left face, which is VERY noticeably different to me, SUDDENLY, and wondered to myself exactly what Shadowfax has written regarding it. It was kind of a trip to come to this site right after( part of my nightly after-work surfings)and see the post addressing it! Whatever it is, it is noticeably different and yes, as a presidential candidate, it needs to be addressed. This has nothing to do with parties, candidates or political bashing. The man has grossly observable physical symptoms. An expanation is in order.
Actually Horner's can involve the forehead.
BTDT
ps - when and if he ever agrees to a debate we will have further evidence.
When you have Horner's the affected side of the forehead will not sweat. Truely.
http://www.ncbi.nlm.nih.gov/pubmed/6478177
The distribution of sweating on the face was studied in 31 patients with Horner's syndrome. In patients whose lesion was known to be distal to the bifurcation of the common carotid artery impairment of sweating was confined to the medial aspect of the forehead and side of the nose. In more proximal lesions loss of sweating involved the whole of one side of the face. Facial sweating was normal in 6 patients with avulsion injuries of the brachial plexus and in 2 patients with a lateral medullary syndrome. These findings suggest that the pattern of sweating in Horner's syndrome may be useful in some patients in localizing the site of the lesion.
Did you take your diagnosis-by-tv boards with Dr. Frist?
If I come into your ER with Bells palsy please don't give me TPA.
The idea of Palin potentially inheriting the presidency is the most unnerving part of this.
It just seems so sad, although this is an interesting discussion. I have no formal medical training and I can see something is going on. While I disagree with his politics my general feeling is McCain is a very decent and honorable man. It's sad to watch him develop medical issues and I only wish him good health. That said, I do think it is valid to ask questions about the health of the folks running for the presidency.
I have remarking in the OR these past few days for people to mark my words. Perhaps it is a CVA, I don't know, but there is definitely something wrong with McCain. From the decisions he has made to the sometimes erratic and slow way he speaks. I don't mean something wrong because he is a Republican either. (Although that may have a lot to do with it!) I don't think he is neurologically fit and that we may begin to see a rapid decline and alteration of his mental state. A pretty scary thought if he gets elected considering his bimbo running mate.
It seems a wildly speculative assertion on your part. Irresponsible even if it is only judged against your own admissions to ignorance.
zcsaooje
Go do a google image search on "John McCain". Fully 10% of the pictures show a detectable eyelid droop on his left side.
ggaodt
Funny part is that according to the history of the wiki article Nurse K posted McCain wasn't added to the list until yesterday
http://en.wikipedia.org/w/index.php?title=Ptosis_(eyelid)&action=history
at least so my mediocre internet savvy has deduced based on the history.
Anyone running for president or VP for that matter should be in exceptional health, and I think the public should be informed on their health.
We are talking about the possible leaders of the free world.
It's funny that you posted this yesterday. I just mentioned his facial droop to my BF. There is something very wrong with McCain.
If he died during his tenure (pray that never happens) look at the bimbo we'd be left with. Did you catch her interview with Katie Couric? That was painful. You could see the disdain on Couric's face.
I think Shadowfax is going a bit off the deep end here:
http://scienceblogs.com/insolence/2008/09/john_mccain_a_dead_man_walking_ptosis.php
And Steve Novella, an honest-to-God neurologist, agrees:
http://www.theness.com/neurologicablog/?p=386
"John McCain has Horner's Syndrome, I'm quite confident. This would be from recurrence of his left temporal melanoma. That is, dysfunction of the sympathetic nerves around his left eye. Others have noticed that most of the observed findings are not brand-new, they are WORSE than before.
That is, the underlyhing problem is progressive. This isn't a stroke; strokes start bad and get better. It isn't Bell's Palsy, which also starts bad and gets better.
If the pattern of findings pointed to a brain lesion, MS could be a possibility. But the symptoms suggest a problem external to the brain.
McCain has developed a swelling at the angle of the jaw on the left, below the ear. This is where one would expect to find lymph node involvement if there were a recurrence of melanoma."
So if McCain has Horner's syndrome, where's the miosis or anhydrosis, which are both also part and parcel of Horner's syndrome? He doesn't have them. As for the swelling at the angle of the jaw, he's had that a long time. It's a normal consequence of melanoma surgery, particularly when he had a large chunk of his face removed, a superficial parotidectomy, and what sounds like a modified radical neck dissection on the left.
It's quite clear to me that you don't have a clue what you're talking about here. The bit on Horner's wasn't that bad, but your speculation about the melanoma was.
Sorry, but I forgot to include this link that describes why the speculation about melanoma recurrence is almost certainly a load of BS:
http://scienceblogs.com/insolence/2008/09/john_mccain_a_dead_man_walking_not_so_fast.php
Orac, do you know how to create a hotlink? The URLs you keep pasting in are getting cut off by the blogging software (at least in my browser).
As I watch the debate, McCain's eyebrow once again works. Maybe the botox lasted longer on the left than on the right haha.
I'm disappointed in you. You must have seen enough old folks presenting with strokes that you should recognize a facial droop when you see one.
I'm a much better nurse than to make sweeping judgments without talking to an A&Ox4 patient prior to screaming "stroke" in a crowded theater. Believe it or not, but I'm a pretty damn good nurse who can sort through stuff with the best of them.
You all had me staring at the left side of McCain's face through the whole debate.
What was most striking to me is his lop-sided sneer, tho I doubt it's indicative of a particular medical condition.
Without looking, I'd have to guees that NK lives in a red state. And drives a red car.
Speculating about an obvious and unexplained medical problem displayed by someone who could possibly become President. Such an outrage! So irresponsible and unpatriotic!
Hey, NK, would that be suggestibility?
He had a superficial parotidecomy where the facial nerve was disected and then reconstruction with a temporal and cervical rotation flap. The nerves are slightly weak from the disection and the movement is secondary to the large rotation of the flap. Dont let political emotion cloud medical judgement.
What this post boils down to is the following:
1) Shadowfax is liberal and was quick to jump to conclusions that will help his guy win and is certainly out-of-line when it comes to what candidates should be expected to disclose and when. Should he have to mention this problem every month? Every week? Every year?
2) You need to know someone's history and the history of the presenting problem (baseline? new?) before you can arrive at an appropriate diagnosis
3) You need to do an exam
4) Reaching conclusions without doing #2 or #3 may make you look like an ass
5) I deserve an apology
I agree with Nurse K. Political hacks don't have the right to do medical diagnosing in their blogs. Actually, I did notice that Senator Obama smokes and his lips appear cyanotic. Are you thinking lung or heart problems?
Throckmorton said:
"He had a superficial parotidecomy where the facial nerve was disected and then reconstruction with a temporal and cervical rotation flap. The nerves are slightly weak from the disection and the movement is secondary to the large rotation of the flap. Dont let political emotion cloud medical judgement."
Then the observed findings could be considered post-surgical Horner's Syndrome, rather than Horner's from melanoma recurrence.
Perhaps so. If so, his symptoms should be stable, not worsening. The observations that led to the original blog post seem to suggest a worsening of McCain's symptoms--worrying.
However, it was hard to observe any of these findings with his debate performance. Eye drops could hide pupil changes and eye redness. Makeup could hide assymetric perspiration. Eyelid droop could also be altered.
Only release of medical records, or independent examination, can really lay these concerns to rest.
Nurse K:
5) I deserve an apology
Maybe the 2,700 doctors that signed a petition to urge McCain to release his medical records also owe you an apology.
Good grief.
http://www.cnn.com/2008/HEALTH/10/08/ftl.mccain.health/index.html
Concerns about McCain's health keep cropping up. From counterpunch.org:
"Is McCain Sicker Than We Know?
A source tells CounterPunch that McCain received grim news during a recent, secret visit to a top cancer hospital in Los Angeles."
The details are only in the print ediction, but the story is discussed online at:
Report: McCain's cancer has metastasised to his lymph nodes
http://www.dailykos.com/storyonly/2008/10/7/122027/106
I find the credibility a bit weak. But it's conceivable that the noted Horner's symptoms improved just before the first debate because of radiation therapy.
Again, only a full release of McCain's records or a complete independent evaluation can settle these questions. Asking for these is very appropriate right now.
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